The amygdala is a paired nuclear complex present in the cerebral hemispheres of vertebrates. It is considered part of the limbic system. It has important role in memory, decision making, and regulating emotions. 1
Sleep deprivation can greatly impact the amygdala, heightening emotional reactivity and impairing the ability to regulate stress and fear responses. Consequently, a sleep-deprived individual may become more easily agitated and may misinterpret neutral social interactions as negative. 2